RNA Details
Disease Name
lipotoxic cardiomyopathy
Tissue
heart
RNA Symbol
Hmgcs2
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
rattus norvegicus
Detection Methods
NA
Target
NA
Pathway
NA
PubMed ID
Title
Exercise Training Reverses Lipotoxicity-induced Cardiomyopathy by Inhibiting HMGCS2
Year
2021
Function
"Exercise-mediated cardioprotection by upregulating miR-344g-5p, which targets Hmgcs2 mRNA, prohibits HMGCS2 upregulation and thus lipotoxicity."